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Food and Drug Administration (FDA) and the European Medicines Agency (EMA) respectively concurred with a pharmaceutical company on the efficacy endpoints for two distinct clinical indications of arhalofenate in 2017
The fact that nrc2 , a mutant affected in GSH2, also exhibited greater sensitivity in its response to AITC confirmed that the root length phenotype was due to the impairment in the glutathione biosynthetic pathway, irrespective of whether GSH1 or GSH2 carried the mutation
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