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Acknowledgements The authors would like to thank Chang Gung Memorial Hospitals for providing Chang Gung Research Database data

As the GLP-1 weight-loss drug market continues to grow, consumers weary of needles now have two options in pill form instead

41 Gastrointestinal symptoms, however, tend to be transient and less severe with proper dose titration

In the longer-term (i.e., 4 weeks), intragastric administration of DB remained effective at increasing meal-induced GLP-1 secretion, associated with a reduction in body weight in obese mice, whereas another bitter tastant, quinine, had minimal effect on GLP-1 or ghrelin, despite reducing body weight (66)