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Persistent glucose elevation damages peripheral nerves and disrupts microvascular circulation

However, our recent investigations have revealed that the Aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor belonging to the b-HLH-PAS family, significantly contributes to the progression of MITF low cells

Given that BSO possesses non-specific pharmacological activities, the authors concluded that this effect was independent of the inhibition of GSH biosynthesis 15