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EXAMPLE 2 preparation of Merrifield Resin and 1- (3-hydroxypropyl) -1H-imidazole solid phase support Referring to the synthesis method of example 1, 1- (3-hydroxypropyl) -1H-imidazole reacts with Merrifield Resin to prepare Merrifield Resin with 1- (3-hydroxypropyl) -1H-imidazole ionic liquid as Linker, and the specific structure is as follows: EXAMPLE 3 preparation of Fmoc-Gly-1- (2-hydroxyethyl) imidazole hexafluorophosphate-Merrifield Resin Weighing 20 g of 1- (2-hydroxyethyl) imidazole hexafluorophosphate-Merrifield Resin prepared in example 1 into a solid phase reaction column, adding DMF, and carrying out bubbling swelling for 60 minutes by nitrogen

Doctors advise caution for LHON patients thinking about Vitamin B12 supplements

A subsequent Danish cohort study of 424,152 patients with type 2 diabetes found roughly a doubling of five-year NAION risk a smaller effect, but in the same direction

Caruso U, Leone L Cravotto E Nava D