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69% have been using the medication for fewer than two years and 53% expect to discontinue use in less than two more years 77% who had discontinued a GLP-1 medication said they were satisfied with the weight loss they experienced, but 90% were on the drug for less than one year Primary barriers to continued use: 76% note side effects

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[9] Rauwolscine (alpha-yohimbine) : This stimulant from the yohimbe tree can boost fat burning and workout performance, but it also raises blood pressure and heart risks if misused, which makes it risky, unpredictable, and not worth gambling your health