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Vitamin B12 keeps the bodys blood cells and nerves healthy, and also helps to make DNA, the genetic material within cells

All the energy metabolic pathways require the presence of NAD+ as a coenzyme to function properly

doi:10.1007/s12257-015-0018-z Xu G, Zhang L, Chen Y, Cheng W, Guo Y, Wei Y, Liang J, Tan W (2015) Saccharomyces cerevisiae microbial preparation with high yield of glutathione and preparation method thereof

Inhibiting the enzyme therefore has consequences on two fronts at once: it spares S-adenosylmethionine, and it leaves nicotinamide available to other routes, including the salvage pathway that supplies NAD