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Their weight remained relatively stable, which may reflect engagement in alternative weight-loss efforts post-discontinuation

The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

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You could try every day for a week and see if that improves the situation