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The investigators concluded that decreased hepatic GSH concentrations in patients with liver disease may represent a contributing factor of liver injury susceptibility and toxicity risk in these patients
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10.1186/s13059-024-03464-8 14 GongL.ShenX.HuangN.WuK.LiR.LiuY.et al (2024)
Canagliflozin 300 mg led to a 3.6 kg weight loss (4.2%) over 104 weeks in type 2 diabetes patients on metformin [39]
This psychological anchoring dramatically improves medication adherence, and research demonstrates that consistent adherence produces better weight loss outcomes than perfect timing with sporadic doses
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