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Injection of mice with heparinase I/III can reduce lung compliance, increase MMP-7 and MMP-9 expression, and cleave HS in the glycocalyx [70]
For many patients, peptides may represent one component of a broader recovery strategy rather than the entire treatment plan
They can interfere with the peptide's biological activity, introduce unknown contaminants, or cause the entire formulation to degrade prematurely
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