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Unlike the palm-side flexor tendons, extensor tendons lie just beneath the skin without substantial protection

Some patients achieve noticeable improvement after one session, while others may benefit from multiple sessions depending on the degree of skin laxity and treatment goals

Nonetheless, both extraction approaches yielded polyphenol-rich extracts with promising applications as functional food additives and in pharmaceutical formulations (51)

Key outcomes: Mean weight loss: 14.9% (vs 2.4% placebo) 86.4% of participants achieved 5% loss (vs 31.5% placebo) 50.5% achieved 15% loss (vs 4.9% placebo) SELECT (Lincoff et al., NEJM 2023) added the cardiovascular signature: in 17,604 non-diabetic adults with prior CV history, semaglutide 2.4 mg reduced MACE (CV death, MI, stroke) by 20% over 3 years