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Bloodbrain barrier and BCB are guarding systems of the brain formed mainly by endothelial cells, which separate the central nervous system (CNS) from the general circulatory system of the body, protecting the brain from toxic metabolites and pathogens (Zenaro et al., 2017)

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d , BN-PAGE immunoblot on isolated WAT mitochondria from Control mice at ZT2 and ZT14 using an antibody mix against OXPHOS complex subunits (n = 5)