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Wu S, Lu W, Chen Z, Dai Y, Chen K, Zhang S
Phytomedicine Plus 2, 100379
Additional Interventions The agents described in this section have been the focus of preclinical research aimed at determining whether they have the potential to support kidney health
Whilst mutations of the MC4R are a rare genetic cause of obesity, the treatment of two people with POMC deficiency with the MC4R agonist setmelanotide previously resulted in massive weight loss of 51.0 kg and 20.5 kg over 42 and 12 weeks respectively [97], highlighting the potential of this mechanism to support weight loss in obesity
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