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Practical Guidance If you choose to drink on a GLP-1 medication: Keep intake to 1 standard drink (5 oz wine, 12 oz beer, 1.5 oz spirits) maximum on any given day Never drink on an empty stomach pair alcohol with a protein-containing meal Drink water before, during, and after 1:1 ratio Never combine alcohol with insulin or sulfonylurea medications without extra caution Avoid sweetened cocktails (double impact: alcohol + sugar) Do not drink on the day of a dose increase side effects are worst that week The safest recommendation is to eliminate alcohol entirely during active weight loss on a GLP-1

Pharmacists assess: Creatinine clearance (not just serum creatinine) Drug accumulation risk Dosing interval vs dose reduction Because safe therapy depends on how well the body can eliminate the drug

As with glutathione, our natural production of collagen begins to decline in our mid-20s

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