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When treating pregnant patients with obesity, it is important to weigh the risks of obesity itself against any potential risks and benefits of prescribing a weight loss medication

In this pooled analysis of patients with heart failure and preserved ejection fraction across the SELECT, FLOW, STEP-HFpEF and STEP-HFpEF diabetes trials, semaglutide significantly reduced the risk of cardiovascular death or worsening heart failure as compared with placebo, as well as worsening heart failure events alone, but the effects on cardiovascular death were not significant, Mikhail Kosiborod, MD, FACC, FAHA, cardiologist at Saint Lukes Mid America Heart Institute and professor of medicine at the University of Missouri-Kansas City School of Medicine, said during a presentation

We included preclinical ( in vitro , in vivo ) and human clinical studies on ASD that reported either redox biomarkers and/or clinical outcomes

Mao MQ, Jing J, Miao YJ, Lv ZF