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Trial results vary by drug, dose, baseline weight, adherence, side-effect tolerance, and whether patients can stay on treatment
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CagriSema appears to partially prevent this adaptation, which could translate to more durable weight maintenance over time
Sitagliptin attenuates myocardial apoptosis via activating LKB-1/AMPK/Akt pathway and suppressing the activity of GSK-3beta and p38alpha/MAPK in a rat model of diabetic cardiomyopathy
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