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Improved diastolic function, reduced ventricular wall stress and decreased accumulation of epicardial fat may contribute to the expected favourable outcomes
Once the sequence was known and recombinant expression became routine, native-sequence human IGF-1 became available as a laboratory reagent and, separately, as a licensed protein under the name mecasermin
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Mechanism of action as a GLP-1 receptor agonist, which helps regulate appetite and food intake
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