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Research shows selenium improves t hyroid antibodie s and ultrasound findings for hypothyroid patients: A systematic review and meta-analysis (the highest quality science) showed that selenium supplementation reduced thyroid antibodies for patients on prescription thyroid medication as well as in untreated patients

Occasionally, some people notice mild, body-wide effects in the first day or so: Mild diarrhea or an upset stomach

It is designed to be absorbed more easily by the cells once it reaches them, but it doesn't offer the same level of protection through the digestive tract that liposomal delivery does