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While a constant exposure of quinone is not necessarily representative of an in vivo scenario, it is however, much more representative of an in vitro situation, whereby a constant source of quinone is essentially available in the extracellular media during cell culture 27

For example, broccoli is a good source of glucoraphanin, the glucosinolate precursor of sulforaphane, and sinigrin, the glucosinolate precursor of allyl isothiocyanate

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709 These findings underscore the potential of targeting the ACSL4-LOX axis as a therapeutic strategy for diseases associated with ferroptosis