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As proof-of-concept, we show that alginate-encapsulated engineered cells implanted in C3H/HeJ male mice can translate circadian inputs or clinically licensed MTNR1A agonists into regulated GLP-1 expression as a therapeutic output exclusively secreted during nighttime, highlighting potential as an experimental cell therapy for obesity-dependent type-2 diabetes

Provide the last-dose details to the surgeon, anesthetist, PCP, and pharmacy

Basith, S., Manavalan, B., Hwan Shin, T

Unlike treatments that only reduce fat, a tummy tuck addresses the combination of skin laxity, soft tissue stretch, and muscle separation that often follows pregnancy, significant weight loss, aging, or genetics