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The initial rates of pNP formation by the [C-RML][ S 1 ] and [C-TLL][ S 1 ] biofluids were estimated at 0.040.01 and 0.020.007 mol min 1 mg 1 (Table 2), respectively, which suggested that the mesophile-derived [C-RML][ S 1 ] biofluid was more effective at physiological temperatures

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Orforglipron showed stronger effects on blood sugar control, HDL cholesterol, and systolic blood pressure, while semaglutide showed larger effects on total body weight, waist circumference, and LDL cholesterol