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The MHRA and EMA have reviewed this evidence, and the Summary of Product Characteristics (SmPC) for semaglutide (Ozempic, Wegovy) specifically advises that patients with diabetic retinopathy should be closely monitored during treatment, particularly during periods of rapid glycaemic improvement

some patients feel more focused and alert, while others experience mild fatigue as their bodies adapt to lower calorie consumption

And I use that analogy when I'm working with patients to really reinforce that it is a chronic relapsing sometimes I don't use disease, people again don't like disease, I'll say condition we can treat it but we don't know exactly how to maintain that healthier body weight without the medication long term in most people

How Patients May Help Reduce the Risk of Side Effects Start With Provider Evaluation Medical evaluation matters before beginning peptide therapy