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Patients using tirzepatide have experienced meaningful reductions in HbA1c, a key marker of long-term glucose control

2021 NEJM) showed that patients on weekly semaglutide lost 14.9% of body weight at 68 weeks, and the protocol allowed for occasional missed doses without protocol violation

Women using oral contraceptives should use a non-oral contraceptive method or add a barrier method for 4 weeks after starting tirzepatide and for 4 weeks after each dose increase, as tirzepatide may reduce oral contraceptive effectiveness

After reaching their goal weight on 12mg, they gradually reduce to 8mg or even 4mg as a maintenance dose