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As a dual-agonist , tirzepatide amplifies the bodys natural responses, leading to better control of blood sugar levels and promoting weight loss
A newer drug of this class is semaglutide (sold under the brand name Wegovy), which was approved in 2021 and was found, on average, to reduce weight by 15% in one clinical trial where people took the drug for 68 weeks
Corticotropin-releasing hormone and the sympathoadrenal system are major mediators in the effects of peripherally administered Exendin-4 on the Hypothalamic-Pituitary-Adrenal axis of male rats
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