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The men who typically see the best gym results are those in their late 30s, 40s, and 50s who've noticed their recovery isn't what it used to be, their gains have plateaued despite consistent training, or they're carrying more body fat than they used to despite the same effort

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However, clinical trials and real-world evidence consistently show that weight reduction with GLP-1RAs is accompanied by decrease in lean body mass, raising concern in patients already predisposed to muscle wasting and underscoring the need for integrated management strategies