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Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults
Strongest clinical weight loss data of any drug tested to date, with liver fat reduction exceeding 80% in MASLD subgroups
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While this has improved accessibility for chronic diabetic patients, it has simultaneously enabled the "off-label" use for weight loss among the general public
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