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Excess accumulated body fat causes mitochondrial dysfunction, inflammation, hyperlipidemia, and insulin resistance, leading to various metabolic health problems (Wiechert and Holzapfel, 2021)

As a new form of cell death, it provides new research directions for the treatment and thinking of many diseases

FOXO4-DRI enhances tissue rejuvenation By clearing out senescent cells, FOXO4-DRI can cause a significant increase in the regeneration of tissues and may restore their functionality, making it a promising agent for reversing cellular aging effects (4)

Research has explored its involvement in circadian rhythm regulation, telomerase activity, and pineal function, including effects on melatonin signaling