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STEP-HFpEF Trials and Study Design The STEP-HFpEF and STEP-HFpEF DM trials evaluated once-weekly semaglutide treatment versus placebo in patients with obesity-related HFpEF, without and with diabetes, respectively
If electrolytes are truly optimal and palpitations persist beyond 8 weeks, request a 24-hour Holter monitor to quantify ectopic beat burden and rule out sustained arrhythmias
That is why in studies they are combined, mapping the whole GHIGF-1 axis
The combined activation results in greater energy expenditure and fat mobilisation than single or dual agonists in preclinical models
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