tirzepatide cause gallstones and Gallstones: Safety Guide What are gallstones? Gallstones are

For the day 1 clinical measure scores (MADRS, QIDSSR, M3VAS, SHAPS, TEPS-A and TEPS-C), linear mixed-effects models were also used with condition (placebo and naltrexone), time (preinfusion and day 1 postinfusion), visit (visit 1 and visit 2) and the interaction between condition and time as fixed effects

10.1177/1179546817739523 23 DonnellanE.WazniO.KanjM.HusseinA.BaranowskiB.LindsayB.et al (2019)

Side Effects and Safety Profile Like most incretin agonists, retatrutide can produce mild to moderate gastrointestinal side effects during dose escalation

In Phase 2 data published in The New England Journal of Medicine , retatrutide reached up to about 24.2% mean body weight reduction at 48 weeks at the highest dose