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The trial was conducted in accordance with the Declaration of Helsinki [34] and the International Conference on Harmonization Good Clinical Practice guidelines [35]

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Who Should Not Take Semaglutide Semaglutide should not be used in individuals who: Have type 1 diabetes Have diabetic ketoacidosis Have a personal or family history of medullary thyroid carcinoma Have MEN 2 Have known hypersensitivity to semaglutide Patients with severe gastrointestinal disease should discuss risks carefully with their specialist

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