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5-Amino-1MQ instead removes a drain on that route: by inhibiting NNMT it prevents nicotinamide from being methylated to 1-methylnicotinamide, leaving it available for NAMPT and the salvage pathway, and simultaneously spares the S-adenosyl-L-methionine that the methylation would have consumed
Clear is expected for non-B12 formulations
Low B12 has been associated with sleep disturbances and with mood symptoms such as low mood or anxiety, and correcting a confirmed deficiency may help some people in these areas
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