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Patients should receive clear written and verbal information about: Expected side effects of each medication Warning signs requiring immediate medical attention (severe abdominal pain, persistent vomiting, signs of pancreatitis, mood changes, suicidal thoughts) The importance of adherence to prescribed doses Lifestyle modifications to support treatment goals Multidisciplinary coordination may be beneficial, particularly when care involves both smoking cessation services and weight management clinics
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[3] [5] The International Olympic Committee (IOC) consensus statement on dietary supplements notes that only caffeine, creatine, buffering agents, and nitrate have good evidence of performance benefit, and none require IV administration
According to ICH Q2(R1) guidelines, the accuracy studies were performed using three levels of concentrations, i.e., 80%, 100% and 120%, by replicate analysis ( n = 3)
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