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individuals with obesity are 35 times more likely to develop OA [75], and most OA patients undergoing total joint replacement surgery for end-stage OA have obesity or are overweight [76]
Insurance coverage for tirzepatide is limited and often requires extensive documentation, prior authorizations, and step therapy failures before approval
The most frequent issues reported from the phase 3 studies are nausea (19%), fatigue (6%), skin darkening (4%), dizziness (4%), and the development of moles (4%)
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