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They are also beneficial for those with type 2 diabetes, as they address both blood sugar levels and weight concerns
As of April 2026, semaglutide remains on the shortage list, but Novo Nordisk has reported to the FDA that manufacturing capacity will meet projected U.S
In the Actos Now for Prevention of Diabetes (ACT NOW) study, pioglitazone decreased the rate of conversion of subjects from having impaired glucose tolerance (IGT) to T2DM by 72% and significantly improved insulin sensitivity and -cell function [30]
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