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Some people benefit from weekly or biweekly injections during high-stress periods, frequent travel, or when recovering from illness

nitrous oxide exposure can inactivate B12 Important: Do not take folic acid alone when B12 deficiency is possible or uncorrected, as this may worsen neurological damage Avoid measuring serum B12 immediately after injections due to falsely high results Dietary optimisation remains the preferred approach for those without absorption issues

In monkeys and in rats, the common response to stressors is the increase of adrenocorticotropic hormone (ACTH) and cortisol plasma levels

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