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JAMA 276 , 19571963 (1996)
Moderate deficiency may include obvious macrocytic anemia, glossitis, as well as some mild or subtle neurological features, such as distal sensory impairment.[] Severe deficiency is characterized by bone marrow suppression, neurological features, and the risk of cardiomyopathy
This balance, however, will be disrupted if there is an increase in ROS production or a decrease in cell antioxidant capacity, resulting in oxidative stress (46, 47)
Preferred sites: lower abdomen (2 inches either side of the navel), outer thigh, love-handle area
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