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Whilst the NHS notes that taking up to 2,000 micrograms daily is unlikely to cause harm in most people, there is generally no benefit to consuming such excessive amounts unless treating confirmed deficiency under medical supervision

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If we consider all the rare heterozygous CNV deletions as pathogenic loss-of-function variations together with the homozygous duplication, we counted seven PD cases each carrying one rare pathogenic deletion

van Eijk, M., Boerefijn, S., Cen, L., Rosa, M., Morren, M., van der Ent, C.K., et al., Med