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Dominant evidence type Early pharmacology, animal-model work, small human PK/PD studies, and limited clinical-development research
As per WHO, the population of people aged 60 years and older worldwide is expected to double, reaching 2.1 billion by 2050
Metformin toxicity can be categorized into metformin-associated lactic acidosis (MALA), metformin-induced lactic acidosis (MILA), and metformin-unrelated lactic acidosis (MULA) (Rivera et al., 2023)
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