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Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide is a dual agonist it activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors simultaneously

How to Retain Muscle While Taking Weight Loss (GLP-1) Drugs Healthy eating plan (with higher protein) Resistance training Endurance exercise Should You Eat Protein to Prevent Muscle Loss When Taking GLP-1 Drugs

Over time, this change in appetite helps create a sustained calorie deficitcrucial for meaningful weight loss

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