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These effects contribute to appetite suppression and delayed gastric emptying, leading to a feeling of fullness similar to the mechanism of GLP-1 receptor agonists

2 Researchers have been able to show through many studies that GLP-1 indirectly works in the liver by inhibiting glucagon secretion by pancreatic alpha-cells, thereby inhibiting gluconeogenesis and glycogenolysis, thus decreasing hepatic glucose production

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Its also important to take your other medications according to your doctors recommendations to help prevent further damage to your kidneys.