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2016: An RCT in 69 women aged 4060 with mild-moderate knee osteoarthritis found 250 mg L-carnitine three times daily for 8 weeks reduced inflammation biomarkers and visual analog scale pain by 52.67% versus placebo [3][51]
Plus, nausea is a known side effect of semaglutide medications
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While no GLP-1 drug is currently approved for this purpose, early-stage clinical research is exploring whether these agents can complement existing treatments such as buprenorphine, naltrexone, or methadone
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