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Data extraction was undertaken independently by two authors (C.B., L.M.)

Contact Us Promptly If You Notice: Significant swelling, warmth, or hardness at the injection site that worsens after 48 hours rather than improving this can indicate a localized infection A spreading rash, hives, or itching that moves beyond the injection site Shortness of breath, chest tightness, or facial swelling these require immediate attention and a call to 911, not just the spa Intense or persistent nausea and vomiting that does not resolve within a day Numbness, tingling, or palpitations These are not common presentations, but they are the signals the body uses to say something needs attention

Still, that hasnt stopped its rise in popularity across wellness forums, clinical research summaries, and biohacking communities

Therefore, scaffolding is currently attempting to mimic the functions of the original extracellular matrix to the greatest extent possible (George and Pragna, 2022)