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50 L of lysate was mixed with 50 L of CellTiter-Glo reagent in a 96-well plate in triplicate according to the manufacturers instructions

Importantly, preclinical studies demonstrated that the synergistic effect of GIPRAs and GLP-1RAs on body weight requires the GABAergic (GABA refers to gamma-aminobutyric acid) GIPR-expressing neurons in the CNS [21, 28]