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Pharmacological interventions such as orlistat or GLP-1 receptor agonists may be considered for patients with BMI 30 kg/m who have not achieved adequate weight loss through lifestyle measures alone
Empower Pharmacy [Product Monograph]
AOD 9604 does not interact with growth hormone receptors, does not affect insulin signaling, and does not cross into the central nervous system to alter appetite or mood
A 2025 European Journal of Clinical Nutrition commentary on the NICE guideline argued that the diagnostic threshold and clinical awareness still need to be tightened further, especially around pernicious anaemia, which is still under-recognised in primary care
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