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PMID: 34687865 Cell Rep Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling

Dermatologically tested and FDA approved: Ensuring safety and efficacy.

To address this gap, the present study adopts a dual approach: (1) evaluating preclinical (animal) studies to elucidate the mechanisms by which curcumin may relieve DACD-related emotional symptoms, and (2) conducting a meta-analysis of human clinical trials to assess its therapeutic efficacy