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PLoS ONE 9:e100832 Agarwal A, Virk G, Ong C, du Plessis SS (2014) Effect of oxidative stress on male reproduction

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Based on the current level of evidence, other authors have also suggested the use of oral or topical glutathione as an adjunctive therapy for facial melanosis

36 As stated in the introduction, in addition to its effects on prostaglandin production, the potential adverse effects of paracetamol in the developing lung have been associated with CYP2E1, the enzyme responsible for metabolizing paracetamol to the reactive metabolite NAPQI