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Feeling constantly tired and lethargic can indicate a lack of vitamin B12
In the study Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin , it was found that providing calcium supplementation to people taking metformin, was able to help prevent metformin-induced vitamin B12 deficiency
If your B12 deficiency is not diet-related, you'll need to take B12 injections
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