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doi: 10.1016/j.jsbmb.2014.01.009

These include: Nausea Vomiting Diarrhea Constipation Stomach pain Loss of appetite Serious side effects Less common but more serious side effects of semaglutide may include: Pancreatitis (inflammation of the pancreas) Kidney problems Gallbladder problems Hypoglycemia (low blood sugar) Diabetic retinopathy Hypersensitivity reactions (such as rash, hives, or difficulty breathing) Most of semaglutides side effects are short-lived, going away once your body gets used to the medication dosage