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The STEP trials evaluated dose escalation, tracked side effects, and assessed long-term durability
Known risks include multiple pregnancies (eg, twins or triplets) and related pregnancy complications, as well as side effects in the female partner when ovulation-inducing drugs are used
Evidence suggests that GLP-1 signaling may mediate inflammatory pathways involved in some metabolic, pulmonary and neurologic disorders
Serious side effects: have included pancreatitis, gallbladder disease, acute kidney injury, hypoglycemia, and severe allergic or injection-site reactions
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