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4 The multiscale anticancer mechanisms of SFN: beyond Nrf2 and HDAC inhibition While the activation of Nrf2-mediated antioxidant response and inhibition of HDACs represent well-established mechanisms underlying SFNs anticancer properties, emerging evidence reveals a far more complex pharmacological profile

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After 72 h of dialysis, the resulting solution was freeze-dried by using low-temperature freeze dryers, yielding P3 (0.62 g), which was obtained as a white powder