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Beyond these three papers, review articles referencing the human peptides discovery in the 1970s continue to shape how researchers frame new hypotheses, particularly around why plasma concentration declines with age and what that means for tissue-repair capacity over time
10.1146/annurev.pharmtox.47.120505.105122 Annu
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Moreover, insulin-like growth factor binding protein related proteins (IGFB- PrPs) have been recently characterized, which aid the metabolic effects of the hormone but their role remains unclear [8]
